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菓子野 康浩 (かしの やすひろ)

  メールアドレス;kashino(at)sci.u-hyogo.ac.jp。【(at)を@に書き換えてください】
理学博士
宮崎県出身
履歴_ルンビニ幼稚園、菓子野小学校、庄内中学校、都城西高校、東京大学教養学部基礎科学科、東京大学大学院理学系研究科、日本学術振興会特別研究員、姫路工業大学理学部助手、兵庫県立大学大学院生命理学研究科助手、兵庫県立大学大学院生命理学研究科准教授
趣味;愛犬との散歩。ガーデニング。くるま。自転車。野山の散策。スキー。スノーボード。テニス。バドミントン。水泳。ウィンドサーフィン。音楽を聴くこと。。。。。
e-mail;kashino[at]sci.u-hyogo.ac.jp


お知らせ

JST/ALCAの実用技術化プロジェクトに採択されました(2016年7月)。
   「珪藻のフィジオロミクスに基づく褐色のエネルギー革命」

    研究期間:2016年8月から2019年度

新エネルギー・産業技術総合開発機構(NEDO)の「新エネルギーベンチャー技術革新事業/新エネルギーベンチャー技術革新事業(バイオマス)」に採択されました(2011年10月)。
   「珪藻を主軸とした低炭素社会実現のための大規模培養からバイオ燃料生産に至る技術開発」

    研究期間:2014年11月から2015年9月(フェーズA)、2015年10月から2016年5月(フェーズB)
    委託先名:イーエス・テクノロジー株式会社、兵庫県立大学、京都大学

科学技術振興機構(JST)の戦略的創造研究推進事業「先端的低炭素化技術開発(ALCA)」に採択されました(2014年11月)。
   「珪藻のフィジオロミクスに基づく褐色のエネルギー革命」

    研究期間:2011年10月から2016年度



おもな研究内容

フィジオロミクス(Physiolomics)

フィジオロミクスの提唱
フィジオロミクスとは

光合成

光合成電子伝達反応の原子レベルでの解明
光化学系II反応中心複合体の生化学
珪藻の光化学系IIおよび光化学系I
Washington University in St. LouisのProf. Pakrasiとの共同研究

光合成生物の環境応答

極域藻類・アイスアルジー・珪藻の生理生化学

極域藻類の生理生化学。
国立極地研究所との共同研究

カナダの北極圏、Baffin湾における不凍海域Polynyaの生態系についての国際共同研究。
North Water Polynya Research Project

カナダの北極圏、マッケンジー川河口域の生態系についての国際共同研究。
CASES(the Canadian Arctic Shelf Exchange Study)における研究
CASES project


次世代水素触媒共同研究センター

水素酵素研究グループ


いくつかの研究発表論文の内容




大学院入試案内



最近の発表論文

菓子野康浩
近赤外光利用型天然光化学系IIの構造と機能
アグリバイオ、3 (3) pp 259-262 (2019)

菓子野康浩、伊福健太郎
「珪藻のフィジオロミクスに基づく褐色のエネルギー革命」のためのパイロットプラント完成
クリーンエネルギー、vol. 27, No. 9, pp 29−35 (2018)

Endo Y, Hatanaka T, Maeda K, Arafune K, Yamamoto T, Itoh K, Kuramochi H, Kashino Y, Ifuku K
Use of ethanol with triolein for fatty acid ethyl ester as biodiesel fuel in a Novozym® 435 fixed-bed reactor
Biomass and Bioenergy 108, pp.433-438 (2018)
Impact Factor; 3.219 (5-Year IF: 4.186)

菓子野康浩、伊福健太郎
珪藻のバイオファクトリー化を目指した基盤技術の開発
化学と生物, vol.55, No. 11, pp 759-766, 2017

伊福健太郎、菓子野康浩
実用珪藻 Chaetoceros 属の新しい応用利用に向けた技術開発
ケミカルエンジニヤリング 特集「バイオサイエンスを支える革新技術」62 (9): 15-21 (2017) .

前田 光治、伊藤 和宏、菓子野 康浩、伊福健太郎、新船幸二、山本拓司
ツノケイソウ液の凍結濃縮操作
化学工学論文集 44(1) : 18-22 (2018) .


Stereochemical assignment of a unique electron acceptor, polar analogue of vitamin K1 (5´-hydroxyphylloquinone), in Photosystem I.
Biosci Biotechnol Biochem 72: 3180-3188. (2017)
Impact Factor; 0.889

Tokushima H, Inoue-Kashino N, Nakazato Y, Masuda A, Ifuku K & Kashino
Advantageous characteristics of the diatom Chaetoceros gracilis as a sustainable biofuel producer.
Biotechnol Biofuels 9: 235 (2016).
Impact Factor; 6.444

Fukunaga Y, Nakajima E, Hatano E, Itoh S, Kashino Y, Miyazawa A
Activation of NMDA receptors thickens the postsynaptic density via proteolysis.
Neurosci Res 101: 6-14 (2015).

Ishihara T, Ifuku K, Yamashita E, Fukunaga Y, Nishino Y, Miyazawa A, Kashino Y, Inoue-Kashino N
Utilization of light by fucoxanthin-chlorophyll-binding protein in a centric diatom, Chaetoceros gracilis.
Photosynth Res 126: 437-447 (2015).

Ifuku K, Yan D, Miyahara M, Inoue-Kashino N, Yamamoto YY & Kashino Y
A stable and efficient nuclear transformation system for the diatom Chaetoceros gracilis.
Photosynth Res 123: 203-211 (2014).

Kosugi M, Shizuma R, Moriyama Y, Koike H, Fukunaga Y, Takeuchi A, Uesugi K, Suzuki Y, Imura S, Kudoh S, Miyazawa A, Kashino Y & Kazuhiko S
Ideal osmotic spaces for chlorobionts or cyanobionts are differentially realized by lichenized fungi.
Plant Physiol 166: 337-348 (2014).

Aoi M, Kashino Y, Sato F & Ifuku K
Function and association of CyanoP in photosystem II of Synechocystis sp. PCC 6803.
"Photosynthesis and Artificial Photosynthesis Research" in Res Chem Intermed 40: 3209-3217 (2013).

Islam MR, Watanabe K, Kashino Y, Satoh K & Koike H
Spectral properties of a divinyl chlorophyll a harboring mutant of Synechocystis sp. PCC6803.
Photosynth Res 117: 245-255 (2013).

菓子野 康浩、伊福 健太郎
珪藻のフィジオロミクスに基づくバイオファクトリーの創出
「化学工業」2013年6月号(VOL.64 No.6)特集「低炭素化先端技術の開発と創成」: pp. 29-37(発行:株式会社 化学工業社) (2013).

Kosugi M, Miyake H, Yamakawa H, Shibata Y, Miyazawa A, Sugimura T, Satoh K, Itoh S & Kashino Y
Arabitol provided by lichenous fungi enhances ability to dissipate excess light energy in a symbiotic green alga under desiccation.
Plant Cell Physiolo 54: 1316-1325 (2013).

Miyahara M, Aoi M, Inoue-Kashino N, Kashino Y & Ifuku K
Highly efficient transformation of the diatom Phaeodactylum tricornutum by multi-pulse electroporation.
Biosci Biotechnol Biochem 77: 120936-1-3 (2013).

Kosugi M, Kashino Y, Kudoh S & Imura S
Establishment of an isolation method of Nostoc commune cells free from extracellular polysaccharides (EPS) using Percoll cenrtifugation (in Japanese).
Antarctic Record 56: 285-293 (2013).

Ozawa S, Kosugi M, Kashino Y, Sugimura T & Takahashi Y
5'-Monohydroxyphylloquinone is the dominant naphthoquinone of PSI in the green alga Chlamydomonas reinhardtii.
Plant Cell Physiolo 53: 237-243 (2012).

Sekine F, Horiguchi K, Kashino Y, Shimizu Y, Yu L-J, Kobayashi M & Wang Z-Y
Gene sequencing and characterization of the light-harvesting complex 2 from thermophilic purple sulfur bacterium Thermochromatium tepidum.
Photosynth Res 111: 9-18 (2011).

Miyake H, Komura M, Itoh S, Kosugi M, Kashino Y, Satoh K & Shibata Y
Multiple dissipation components of excess light energy in dry lichen revealed by ultrafast fluorescence study at 5 K.
Photosynth Res 110: 39-48 (2011).

Inoue-Kashino N, Kashino Y and Takahashi Y
Psb30 is a photosystem II reaction center subunit and is required for optimal growth in high light in Chlamydomonas reinhardtii.
J Photochem Photobiol B: Biology 104: 220-228 (2011).

Tanabe Y, Shitara T, Kashino Y, Hara Y and Kudoh S
Utilizing the effective xanthophylls cycle for blooming of Ochromonas smithii and O. itoi (Chrysophyceae) on the snow surface.
PloS ONE 6: e14690 (2011).

Inoue-Kashino N, Kashino Y, Orii H, Satoh K, Terashima I and Pakrasi HB
S4 Protein Sll1252 Is Necessary for Energy Balancing in Photosynthetic Electron Transport in Synechocystis sp. PCC 6803.
Biochemistry 50: 329-339 (2011).
Biochemistry Vol 50 Issue 3のcover page high-lighted articleに選ばれました。

Kogo N, Tazaki A, Kashino Y, Morichika K, Orii H, Mochii M and Watanabe K
Gern-line mitochondria exhibit suppressed respiratory activity to support their accurate transmission to the next generation.
Developmental Biology 349: 462-469 (2011).

Hashihama F, Umeda H, Hamada C, Kudoh S, Hirawake T, Satoh K, Fukuchi M and Kashino Y
Light acclimation states of phytoplankton in the Southern Ocean, determined using photosynthetic pigment distribution.
Mar Biol 157: 2263-2278 (2010).

Sugiura M, Harada S, Manabe, Hayashi, Kashino Y and Boussac A
Psb30 contributes to structurally stabilise the Photosystem II complex in the thermophilic cyanobacterium Thermosynehcococcus elongatus.
Biochim Biophys Acta 1797: 1546-1554 (2010).

Kosugi M, Katashima Y, Aikawa S, Tanabe Y, Kudoh S, Kashino Y, Koike H and Satoh K
Comparative study on the photosynthetic properties of Prasiola (Chlorophyceae) and Nostoc (Cyanophyceae) from Antarctic and non-Antarctic sites.
J Phycol 46: 466-476 (2010).

Kosugi M, Kashino Y and Satoh K
Comparative analysis of light curves of Ramalina yasudae and freshly isolated Trebouxia sp. revealed the presence of intrinsic protection mechanisms independent of upper cortex for the photosynthetic system of algal symbionts in lichen.
Lichenology 9: 1-10 (2010).

Nagao R, Tomo T, Noguchi E, Nakajima S, Suzuki T, Okumura A, Kashino Y, Mimuro M, Ikeuchi M and Enami I
Purification and characterization of a stable oxygen-evolving Photosystem II complex from a marine centric diatom, Chaetoceros gracilis.
Biochim Biophys Acta 1797: 160-166 (2010)

西澤明人、千田美紀、千田俊哉、菓子野康浩、福田雅夫、木村成伸
「貧栄養環境下で芳香族化合物を分解できる新規光合成微生物」
  ケミカルエンジニヤリング 54 (10) 特集=バイオテクノロジーと実用技術: pp. 785-791(発行:株式会社 化学工業社)(2009)

井上(菓子野)名津子、菓子野康浩
SDS-PAGE- 低温科学 67(光合成研究法): 359-372. (2009)

菓子野康浩
Blue-Native PAGE 低温科学 67(光合成研究法): 373-376. (2009)

菓子野康浩
Native-Green PAGE 低温科学 67(光合成研究法): 377-380. (2009)

Ikeya T, Horimoto N and Kashino Y
A practical method for sensitive determination of the fluorescent water-tracer uranine by reversed phase HPLC under alkaline conditions.
Talanta 79: 818-823 (2009).

Takahashi T, Inoue-Kashino N, Ozawa S, Takahashi Y, Kashino Y, and Satoh K
Photosystem II complex in vivo is a monomer.
J Biol Chem 284: 15598-15606 (2009).

Kosugi M, Arita M, Shizuma R, Moriyama Y, Kashino Y, Koike H, and Satoh K
Responses to desiccation stress in lichens are different from those in their photobionts.
Plant Cell Physiol 50: 879-888 (2009).

Aikawa S, Hattori H, Gomi Y, Watanabe K, Kudoh S, Kashino Y, and Satoh K
Diel tuning of photosynthetic systems in ice algae at Saroma-ko Lagoon, Hokkaido, Japan.
Polar Sci 3: 57-72 (2009).

Ooyabu J, Ohtsuka M, Kashino Y, Koike H, and Satoh K
The expression pattern of NAD(P)H oxidases and the cyclic electron transport pathway around photosystem I of Synechocystis sp. PCC6803 depend on growth conditions.
Biosci Biotechnol Biochem 72: 3180-3188 (2008).

Inoue-Kashino N, Takahashi T, Ban A, Sugiura M, Takahashi Y, Satoh K and Kashino Y
Evidence for a stable association of Psb30 (Ycf12) with photosystem II core complex in the cyanobacterium Synechocystis sp. PCC 6803.
Photosynth Res: 323-335 (2008).

Islam MR, Aikawa S, Midorikawa T, Kashino Y, Satoh K and Koike H
slr1923 of Synechocystis sp. PCC 6803 is essential for conversion of 3,8-divinyl(proto)chlorophyll(ide) to 3-monovinyl(proto)chlorophyll(ide).
Plant Physiol 148: 1068-1081 (2008) .

Yamori W, Noguchi K, Kashino Y, and Terashima I
The role of the electron transport in determining the temperature dependence of photosynthetic rate in spinach leaves grown at contrasting temperatures.
Plant Cell Physiol 49: 583 - 591 (2008).

Ikeda Y, Komura M, Watanabe M, Minami C, Koike H, Itoh S, Kashino Y and Satoh K
Photosystem I complexes associated with fucoxanthin-chlorophyll-binding proteins from a marine centric diatom, Chaetoceros gracilis.
Biochim Biophys Acta 1777: 351-361 (2008).

Nagao R, Ishii A, Tada O, Suzuki T, Dohmae N, Okumura A, Iwai M, Takahashi T, Kashino Y and Enami I
Isolation and characterization of oxygen-evolving thylakoid membranes and Photosystem II particles from a marine diatom Chaetoceros gracilis.
Biochim Biophys Acta 1767: 1353-1362 (2007).

Kashino Y, Takahashi T, Inoue-Kashino N, Ban A, Ikeda Y, Satoh K and Sugiura M
Ycf12 is a core subunit in the photosystem II complex.
Biochim Biophys Acta 1767(11): 1269-1275 (2007).

Kashino Y, Harayama T, Pakrasi HB and Satoh K
Preparation of membrane proteins for analysis by two-dimensional gel electrophoresis.
J Chromatogr B 849: 282-292 (2007).

Roose JL, Kashino Y and Pakrasi HB
The PsbQ protein defines cyanobacterial photosystem II complexes with highest activity and stability.
Proc Natl Acad Sci USA 104:.2548-2553 (2007).

Ohnishi N, Kashino Y, Satoh K, Ozawa S and Takahashi Y
Chloroplast-encoded polypeptide PsbT is involved in the repair of primary electron acceptor QA of photosystem II during photoinhibition in Chlamydomonas reinhardtii.
J Biol Chem 282: 7107-7115 (2007).

Kashino Y, Inoue-Kashino N, Roose JL & Pakrasi HB
Absence of the PsbQ Protein Results in Destabilization of the PsbV Protein and Decreased Oxygen Evolution Activity in Cyanobacterial Photosystem II.
J Biol Chem, Jul 2006; 281: 20834-20841 (2006).

Ban A, Aikawa S, Hattori H, Sasaki H, Sampei M, Kudoh S, Fukuchi M, Satoh K & Kashino Y
Comparative analysis of photosynthetic properties in ice algae and phytoplankton inhabiting Franklin Bay, the Canadian Arctic, with those in mesophilic diatoms during CASES 03-04.
Polar Bioscience 19; 11-28 (2006).

Inoue-Kashino N, Kashino Y, Satoh K, Terashima I & Pakrasi HB
PsbU Provides a Stable Architecture for the Oxygen-Evolving System in Cyanobacterial Photosystem II
Biochemistry 44(36): 12214 - 12228 (2005).

Thornton LE., Ohkawa H, Roose JL, Kashino Y, Keren N & Pakrasi HB
Homologs of Plant PsbP and PsbQ Proteins Are Necessary for Regulation of Photosystem II Activity in the Cyanobacterium Synechocystis 6803
Plant Cell 16: 2164-2175 (2004)

Kashino Y
Separation methods in the analysis of protein membrane complexes.
Journal of Chromatography B 797 (1-2): 191-216 (2003)

Kashino Y & Kudoh S
Concerted response of xanthophyll-cycle pigments in a marine diatom, Chaetoceros gracilis, to the sifts of light condition.
Phycological Research 51 (3): 168-172 (2003)

Kudoh S, Imura S & Kashino Y
Xanthophyll cycle of ice algae prevailing in sea ice bottom in Saroma Ko lagoon, Hokkaido, Japan.
Polar Bioscience 16: 86-97 (2003)

Kudoh S, Kashino Y & Imura S
Ecological studies on aquatic moss pillars in Antarctic lakes. 3. Light response and chilling and heat sensitivity of photosynthesis.
Polar Bioscience 16: 33-42 (2003)

工藤栄、菓子野康浩
海氷藻類の生理生態 -サロマ湖での光合成に関する研究例を中心に-
月刊海洋 30: 130-139 (2002)

Kashino Y, Koike H, Yoshio M, Egashira H, Ikeuchi M, Pakrasi HB, Satoh K.
Low-molecular-mass polypeptide components of a photosystem II preparation from the thermophilic cyanobacterium Thermosynechococcus vulcanus.
Plant Cell Physiol 43(11):1366-73 (2002).

Kashino Y, Lauber WM, Carroll JA, Wang Q, Whitmarsh J, Satoh J & Pakrasi HB
Proteomic analysis of a highly active photosystem II preparation from the cyanobacterium Synechocystis sp. PCC 6803 reveals the presence of novel polypeptides.
Biochemistry 41(25):8004-12 (2002).

Kashino Y, Kudoh S, Hayashi Y, Suzuki Y, Odate T, Hirawake T, Satoh K & Fukuchi M
Strategies of phytoplankton to perform effective photosynthesis in the North Water.
Deep Sea Research 49: 5049-5061 (2002).

Sampei, M., Sasaki, M., Hattori, H., Kudoh, S., Kashino, Y., Fukuchi, M.
Seasonal and spatial variability in the flux of biogenic particles in the North Water polynya in 1997-1998.
Deep Sea Research II 49: 5245-5257(2002)

Kashino Y, Koike H & Satoh K
An improved sodium dodecyl sulfate-polyacrylamide gel electrophoresis system for the analysis of membrane protein complexes.
Electrophoresis 22 (6):1004-7 (2001).

Ikeya T, Kashino Y, Kudoh S, Imura S, Watanabe K & Fukuchi M
Acclimation of photosynthetic properties in psychrophilic diatom isolated under different light intensities.
Polar Bioscience 13: 43-54 (2000).

Kashino Y, Fujimoto K, Akamatsu A, Koike H, Satoh K & Kudoh S.
Photosynthetic pigment composition of ice algal and phytoplankton assemblages in early spring in Saroma ko lagoon, Hokkaido, Japan.
Proc. NIPR Symp. Polar Biol., 11: pp.22-32 (1998)

所属学会等

日本植物生理学会
日本植物学会
日本光合成学会
American Society of Plant Physiology
American Chemical Society
International Society of Photosynthesis Research
近畿植物学会

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