研究業績 / publication

Hajime Abe / ORCid = 0000-0002-8433-1530

１．原著論文

  1. Preferential Recognition and Extraction to Pentoses over Hexoses by a D6h-Symmetrical Ethynylphenol Macrocycle with Six Inner Phenolic Hydroxy Groups
    Hayashi, T.; Ohishi, Y.; Abe, H.; Inouye, M.
    J. Org. Chem., 2020, 85, 1927–1934. DOI: 10.1021/acs.joc.9b02639

  2. Enantioselective Solid–Liquid Extraction of Native Saccharides with Chiral BINOL-Based Pyridine–Phenol Type Macrocycles
    Ohishi, Y.; Murase, M.; Abe, H.; Inouye, M.
    Org. Lett., 2019, 21, 6202–6207. DOI: 10.1021/acs.orglett.9b01980

  3. 糖質の認識によりキラルならせんを巻く芳香族フォルダマー (Symposium Review)
    阿部　肇
    薬学雑誌, 2019, 139, 591–598. DOI: 10.1248/yakushi.18-00179-2

  4. Investigation of Receptor-Mediated Cyanocobalamin (Vitamin B12) Transport across the Inner Blood–Retinal Barrier Using Fluorescence-Labeled Cyanocobalamin
    Kinoshita, Y.; Nogami, K.; Jomura, R.; Akanuma, S.; Abe, H.; Inouye, M.; Kubo, Y.; Hosoya, K.
    Mol. Pharmaceutics, 2018, 15, 3583–3594. DOI: 10.1021/acs.molpharmaceut.8b00617

  5. Spontaneous Helix Formation of "meta"-Ethynylphenol Oligomers by Sequential Intramolecular Hydrogen Bonding inside the Cavities
    Hayashi, T.; Ohishi, Y.; So, H.-S.; Abe, H.; Matsumoto, S.; Inouye, M.
    J. Org. Chem., 2018, 83, 8724-8730. DOI: 10.1021/acs.joc.8b00996

  6. Metathesis-Based Stapling of a Pyridine-Acetylene-Phenol Oligomer Having Alkenyl Side Chains after Intermolecular Templation by Native Saccharides
    Abe, H.; Sato, C.; Ohishi, Y.; Inouye, M.
    Eur. J. Org. Chem., 2018, 3131-3138. DOI: 10.1002/ejoc.201800531

  7. Nonplanar Macrocycle Consisting of Four Pyridine and Phenol Units Connected with Acetylene Bonds Displaying Preferential Binding to Maltoside over Monosaccharides
    Ohishi, Y.; Yamamoto, N.; Abe, H.; Inouye, M.
    J. Org. Chem., 2018, 83, 5766–5770. DOI: 10.1021/acs.joc.8b00062

  8. Hexaphenolic Rigid Cages Prepared by Self-Organization of C3v Tridentates
    Abe, H.; Hashikawa, D.; Minami, T.; Ohtani, K.; Masuda, K.; Matsumoto, S.; Inouye, M.
    J. Org. Chem., 2018, 83, 3132–3141. DOI: 10.1021/acs.joc.7b03111

  9. Saccharide Recognition and Helix Formation in Water with an Amphiphilic Pyridine-Phenol Alternating Oligomer
    Ohishi, Y.; Abe, H.; Inouye, M.
    Eur. J. Org. Chem., 2017, 6975-6979. DOI: 10.1002/ejoc.201701522

  10. Helix-Rotaxane Hybrid Systems: Rotaxane-Stabilized, Saccharide-Induced Chiral Ethynylpyridine Helices by a Thermodynamic Process
    Hirokane, S.; Takashima, S.; Abe, H.; Inouye, M.
    Eur. J. Org. Chem., 2017, 726-733. DOI: 10.1002/ejoc.201601323

  11. Preparation and Higher-order Structures of 2,6-Pyridylene and 2,6-Pyrazylene Alternating Macrocycle with the Inner Nitrogen Atoms in All the Aromatic Rings
    Suzuki, D.; Abe, H.; Minami, T.; Matsumoto, S.; Inouye, M.
    Chem. Lett., 2017, 46, 1740-1742. DOI: 10.1246/cl.170815

  12. Kinetic Switching of Achirality/Chirality Memorization of meta-Ethynylpyridine Polymer by Coordination of Cu(II) Outside the Polymer
    Abe, H.; Takashima, S.; Inouye, M.
    Heterocycles, 2017, 95, 730-737. (Prof. Dr. Masakatsu Shibasaki's Special Issue) DOI: 10.3987/COM-16-S(S)64

  13. D3h-Symmetrical Shape-Persistent Macrocycles Consisting of Pyridine-Acetylene-Phenol Conjugates as an Efficient Host Architecture for Saccharide Recognition
    Abe, H.; Yoneda, T.; Ohishi, Y.; Inouye, M.
    Chem. Eur. J., 2016, 22, 18944-18952. DOI: 10.1002/chem.201603987

  14. Discrete Molecular Recognition Induced Higher-Order Structures: Fibrous Formation Triggered by Melamine Recognition with a Cationic Ethynylpyridine Macrocyclic Host
    Suzuki, D.; Abe, H.; Inouye, M.
    Org. Lett., 2016, 18, 320-323. DOI: 10.1021/acs.orglett.5b03502

  15. A D3h-Symmetric Macrocycle Alternatingly Composed of Pyridine and Benzyl Alcohol Units Linked with Acetylene Bonds
    Abe, H.; Yumoto, R.; Inouye, M.
    Heterocycles, 2016, 93, 580-592. (Prof. Dr. Lutz F. Tietze's Special Issue) DOI: 10.3987/COM-15-S(T)44

  16. Native Mannose-Dominant Extraction by Pyridine–Phenol Alternating Oligomers Having an Extremely Efficient Repeating Motif of Hydrogen-Bonding Acceptors and Donors
    Ohishi, Y.; Abe, H.; Inouye, M.
    Chem. Eur. J., 2015, 21, 16504-16511. DOI: 10.1002/chem.201503149

  17. Glycosyl-Templated Chiral Helix Stapling of Ethynylpyridine Oligomers by Alkene Metathesis between Inter-Pitch Side Chains
    Abe, H.; Kayamori, F.; Inouye, M.
    Chem. Eur. J., 2015, 21, 9405-9413. DOI: 10.1002/chem.201501102

  18. A New Class of Structurally Simple and Highly Emissive Fluorophores with a Pyridine–Acetylene–Phenol Conjugate
    Ohishi, Y.; Abe, H.; Inouye, M.
    Heterocycles, 2015, 90, 515-528. (Prof. Dr. Isao Kuwajima's Special Issue) DOI: 10.3987/COM-14-S(K)51

  19. Highly efficient stabilisation of meta-ethynylpyridine polymers with amide side chains in water by coordination of rare-earth metals
    Makida, H.; Abe, H.; Inouye, M.
    Org. Biomol. Chem., 2015, 13, 1700-1707. DOI: 10.1039/C4OB02129K

  20. Alternating 2,6-/3,5-Substituted Pyridine-Acetylene Macrocycles: π-Stacking Self-Assemblies Enhanced by Intermolecular Dipole–Dipole Interaction
    Abe, H.; Ohtani, K.; Suzuki, D.; Chida, Y.; Shimada, Y.; Matsumoto, Y.; Inouye, M.
    Org. Lett., 2014, 16, 828-831. DOI: 10.1021/ol403579e

  21. Preparation and Spectroscopic Study of Alternate meta-Ethynylpyridine Oligomer Involving 2,4,6-Trisubstituted and 3,5-Disubstituted Pyridine Rings
    Abe, H.; Suzuki, D.; Shimizu, A.; Inouye, M.
    Heterocycles, 2014, 88, 547-557. (Prof. Dr. Victor Snieckus's Special Issue) DOI: 10.3987/COM-13-S(S)78

  22. Unexpected chain length dependence on a chiral memory effect of "meta-ethynylpyridine" oligomers
    Takashima, S.; Abe, H.; Inouye, M.
    Tetrahedron: Asymmetry, 2013, 24, 527-531. DOI: 10.1016/j.tetasy.2013.03.019

  23. Stabilization of Chiral Helices for Saccharide-Linked Ethynylpyridine Oligomers Possessing a Conformationally Well-Defined Linkage
    Kayamori, F.; Abe, H.; Inouye, M.
    Eur. J. Org. Chem., 2013, 1677-1682.DOI: 10.1039/C2CC36779C

  24. Improvement of Helix-Forming Ability of Mannoside-Linked Ethynylpyridine Oligomers Constructed by Convergent Synthesis
    Abe, H.; Makida, H.; Inouye, M.
    Heterocycles, 2012, 86, 955-963. (Prof. Dr. Eiichi Negishi's Special Issue) DOI: 10.3987/COM-12-S(N)97

  25. Formation of Higher-Order Structures of Chiral Poly(ethynylpyridine)s Depending on Size, Temperature, and Saccharide Recognition
    Abe, H.; Okada, K.; Makida, H.; Inouye, M.
    Org. Biomol. Chem., 2012, 10, 6930-6936. DOI: 10.1039/C2OB25816A

  26. Concentration- and Time-Dependent Eccentric Changes ofin Circular Dichroism of Saccharide-Linked Ethynylpyridine Oligomer with Copper(II) Ions
    Abe, H.; Ohishi, Y.; Inouye, M.
    J. Org. Chem., 2012, 77, 5209-5214. DOI: 10.1021/jo300735j

  27. Development of Convergent Synthetic Method for Saccharide-Linked Ethynylpyridine Foldamers by Huisgen Reaction
    Abe, H.; Makida, H.; Inouye, M.
    Tetrahedron, 2012, 68, 4353-4361. DOI: 10.1016/j.tet.2012.02.069

  28. Copper(II)/phenanthroline-mediated CD-enhancement and Chiral Memory Effect on meta-Ethynylpyridine Oligomer
    Takashima, S.; Abe, H.; Inouye, M.
    Chem. Commun., 2012, 48, 3330-3332. DOI: 10.1039/C2CC00063F

  29. Palladium-Catalyzed Selective and Sequential Functionalization of 2,4,6-Trihalopyridine Rings: Synthesis of Ethynylpyridine Polymers Directly Joined with aza-Crown Ethers
    Takashima, S.; Yamamoto, T.; Abe, H.; Inouye, M.
    Heterocycles, 2012, 84, 355-360. (Prof. Dr. Albert Padwa's Special Issue) DOI: 10.3987/COM-11-S(P)62

  30. Copper(II)-Mediated Chiral Helicity Amplification and Inversion of meta-Ethynylpyridine Polymers with Metal Coordination Sites
    Takashima, S.; Abe, H.; Inouye, M.
    Chem. Commun., 2011, 47, 7455-7457.DOI:10.1039/C1CC12358K

  31. Selective Binding of D2h-Symmetrical, Acetylene-Linked Pyridine/Pyridone Macrocycles to Maltoside
    Abe, H.; Chida, Y.; Kurokawa, H.; Inouye, M.
    J. Org. Chem., 2011, 133, 3366-3371.DOI: 10.1021/jo2003055

  32. Preparation of Ethynylpyridine Macrocycles by Oxidative Coupling of an Ethynylpyridine Trimer with Terminal Acetylenes
    Abe, H.; Kurokawa, H.; Chida, Y.; Inouye, M.
    J. Org. Chem., 2011, 76, 309-311. DOI: 10.1021/jo101921e

  33. Hexamethyldisilazane-Promoted Sonogashira Reaction of Polyfunctionalized N-Containing Heterocycles
    Inouye, M.; Doi, Y.; Azuchi, J.; Shirato, W.; Chiba, J.; Abe, H.
    Heterocycles, 2011, 82, 1137-1141. (Prof. Dr. Albert Eschenmoser's Special Issue) DOI: 10.3987/COM-10-S(E)89

  34. Azacrown-attached meta-ethynylpyridine polymer: saccharide recognition regulated by supramolecular device
    Abe, H.; Takashima, S.; Yamamoto, T.; Inouye, M.
    Chem. Commun., 2009, 2121-2123. DOI: 10.1039/b902269d

  35. Saccharide-Linked Ethynylpyridine Oligomers: Primary Structures Encode Chiral Helices
    Abe, H.; Murayama, D.; Kayamori, F.; Inouye, M.
    Macromolecules, 2008, 41, 6903-6909. DOI: 10.1021/ma801470r

  36. D3h-Symmetrical Hydrogen-Bonding Unit as a Saccharide Recognition and Self-Assembling Module
    Abe, H.; Horii, A.; Matsumoto, S.; Shiro, M.; Inouye, M.
    Org. Lett., 2008, 10, 2685-2688. DOI: 10.1021/ol800783a

  37. Saccharide Recognition-Induced Transformation of Pyridine-Pyridone Alternate Oligomers from Self-Dimer to Helical Complex
    Abe, H.; Machiguchi, H.; Matsumoto, S.; Inouye, M.
    J. Org. Chem., 2008, 73, 4650-4661. DOI: 10.1021/jo800599w

  38. Translation of Mutarotation into Induced CD Signals Based on Helix Inversion of Host Polymers
    Waki, M.; Abe, H.; Inouye, M.
    Angew. Chem., Int. Ed., 2007, 46, 3059-3061. DOI: 10.1002/anie.200604176

  39. Helix Formation in Synthetic Polymers by Hydrogen Bonding with Native Saccharides in Protic Media
    Waki, M.; Abe, H.; Inouye, M.
    Chem.-Eur. J., 2006, 12, 7639-7647. DOI: 10.1002/chem.200600315

  40. Regulation of Saccharide Binding with Basic Poly(ethynylpyridine)s by H+-Induced Helix Formation
    Abe, H.; Masuda, N.; Waki, M.; Inouye, M.
    J. Am. Chem. Soc., 2005, 127, 16189-16196. DOI: 10.1021/ja054134u

  41. Tautomeric Self-Dimerization and Molecular Recognition Properties of 2-Aminopyrimidinone Derivatives as Triple Hydrogen-Bonding Modules in Molecular Assemblies
    Abe, H.; Takase, M.; Doi, Y.; Matsumoto, S.; Furusyo, M.; Inouye, M.
    Eur. J. Org. Chem., 2005, 2931-2940. DOI: 10.1002/ejoc.200500010

  42. A Rigid C3v-Symmetrical Host for Saccharide Recognition: 1,3,5-Tris(2-hydroxyaryl)-2,4,6-trimethylbenzenes
    Abe, H.; Aoyagi, Y.; Inouye, M.
    Org. Lett., 2005, 7, 59-61. DOI: 10.1021/ol047907c

  43. Saccharide-Dependent Induction of Chiral Helicity in Achiral Synthetic Hydrogen-Bonding Oligomers
    Inouye, M.; Waki, M.; Abe, H.
    J. Am. Chem. Soc. 2004, 126, 2022 - 2027. DOI: 10.1021/ja039371g

  44. Synthesis and Molecular Recognition of Pyrenophanes with Polycationic or Amphiphilic Functionalities: Artificial Plate-Shaped Cavitant Incorporating Arenes and Nucleotides in Water
    Abe, H; Mawatari, Y.; Teraoka, H.; Fujimoto, K.; Inouye, M.
    J. Org. Chem. 2004, 69, 495 - 504. DOI: 10.1021/jo035188u

  45. Stereoselective Synthesis of Alkynyl C-2-Deoxy-β-D- ribofuranosides via Intramolecular Nicholas Reaction: A Versatile Building Block for Nonnatural C-Nucleosides
    Takase, M; Morikawa, T.; Abe, H.; Inouye, M.
    Org. Lett. 2003, 5, 625 - 628. DOI: 10.1021/jo0264473

  46. Pd-Catalyzed Asymmetric Hydrogenation of α-Fluorinated Iminoesters in Fluorinated Alcohol: A New and Catalytic Enantioselective Synthesis of Fluoro α-Amino Acid Derivatives
    Abe, H.; Amii, H.; Uneyama, K.
    Org. Lett., 2001, 3, 313 - 315. DOI: 10.1021/ol0002471

  47. Copper-mediated Nucleophilic Substitution of 1-Haloalkynes. Halogen Exchange and Sulfonylation
    Abe, H.; Suzuki, H.
    Bull. Chem. Soc. Jpn., 1999, 72, 787 - 798.
  48. A New Straightforward Synthesis of Alkynyl Sulfones via the Sonochemical Coupling between Alkynyl Halides and Copper Sulfinates
    Suzuki, H.; Abe, H.
    Tetrahedron Lett., 1996, 37, 3717 - 3720.
  49. Copper(I)-mediated Novel Thiocyanation of Nonactivated Aryl Iodides
    Suzuki, H.; Abe, H.
    Synth. Commun., 1996, 26, 3413 - 3419.
  50. Copper-Assisted Displacement Reaction of Nonactivated Iodoarenes with Arenesulfinates. Convenient Alternative Synthesis of Unsymmetrical Diaryl Sufones
    Suzuki, H.; Abe, H.
    Tetrahedron Lett., 1995, 36, 6239 - 6242.
  51. A Simple Cyclization Route to Some 4-Substituted 3-Aminoisoquinolines
    Suzuki, H.; Abe, H.
    Synthesis, 1995, 763 - 765.
  52. A Novel Cyclization Route to Some Substituted 3(2H)-Isoquinolinones
    Suzuki, H.; Abe, H.; Thiruvikraman, S. V.
    J. Org. Chem., 1994, 59, 6116 - 6118.

２．総説・解説

  1. meta-エチニルピリジンポリマー・オリゴマーの機能化によるらせん構造の安定化
    阿部肇，大石雄基，井上将彦
    有機合成化学協会誌 2016, 74, 254-265.

  2. 星の上を歩く王冠（注目の論文）
    阿部肇
    化学 2010, 65, 64-65.

  3. 分子内エキシマー（十字路）
    阿部肇
    有機合成化学協会誌 2010, 68, 171.

  4. 糖質を認識する高分子「エチニルピリジンポリマー」の開発
    阿部肇，井上将彦
    有機合成化学協会誌 2010, 68, 112-123.

  5. 疎水性ポケット分子によるヌクレオチド認識の現状と将来
    阿部肇, 井上将彦
    未来材料 2003, 3, 28 - 34.

３．成書

  1. 「先端化学シリーズIII」日本化学会編
    井上将彦, 阿部肇
    丸善 2003, pp 91 - 97.

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